ACIDOSIS ACTIVATES THE NRF2 PATHWAY IN RENAL PROXIMAL TUBULE-DERIVED CELLS THROUGH A CROSSTALK WITH RENAL FIBROBLASTS

Acidosis Activates the Nrf2 Pathway in Renal Proximal Tubule-Derived Cells through a Crosstalk with Renal Fibroblasts

Crosstalk of renal epithelial cells with interstitial fibroblasts plays an important role in kidney pathophysiology.A previous study showed that crosstalk between renal epithelial cells and renal fibroblasts protects against acidosis-induced damage.In order to gain further mechanistic insight into this crosstalk, we investigated the effect of acido

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The Text4HealthyAging Program: An Evidence-Based Text Messaging Innovation to Support Healthy Urban Aging in Canada and Australia

Age-friendly cities are crucial to achieve the WHO goal of healthy aging.Such cities promote opportunities for health, participation, and security, thus enhancing quality of life as people age.Older people commonly experience psychosocial challenges such as anxiety, depression, substance abuse, loss of autonomy, grief, fear, and Icemaker Thermostat

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Sequential Immune Acquisition of Monoclonal Antibodies Enhances Phagocytosis of Acinetobacter baumannii by Recognizing ATP Synthase

Objectives: The aim of this study was to prepare monoclonal antibodies (mAbs) that broadly target Acinetobacter baumannii and protect against infection by multi-drug-resistant (MDR) A.baumannii from different sources.Methods: mAb 8E6 and mAb 1B5 were prepared by sequentially immunizing mice with Icemaker Thermostat a sublethal inoculation of three

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Experimental and Numerical Study of Heptane Pool Fire

The need for sustainability and a smaller ecological footprint lead to the construction of more airtight building envelopes with better thermal insulation to increase energy efficiency according to the Energy Performance of Buildings Directive (EPBD 2010/31/EU).However, specific fire risks can be encountered by the occupants since they can be block

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